Progress in understanding the genetics of bronchopulmonary dysplasia

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Bronchopulmonary Dysplasia

Bronchopulmonary dysplasia (BPD) continues to be the most common and most important complication in preterm infants with RDS. The incidence varies from 20 to 60 % in preterm infants whose weight are < 1500 gram. The presence of BPD is often associated with significant mortality and short term and long term morbidity, including growth failure and neurodevelopment delay. The exact mechanism and p...

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Bronchopulmonary dysplasia.

Bronchopulmonary dysplasia (BPD) is the most common chronic respiratory disease that results from complications related to the lung injury during the treatment of respiratory distress syndrome, or develops in older infants when abnormal lung growth occurs. The definition and classification of BPD have changed since the original diagnosis was established many years ago. The incidence of BPD cont...

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Bronchopulmonary dysplasia.

Introduction Many advances in neonatology in the last several decades have allowed for the resuscitation, support, and survival of more preterm infants. The mortality associated with respiratory disease in this population of micropremies has been altered significantly by the use of antenatal corticosteroids, postnatal surfactant, improved respiratory support technology, and enhanced nutritional...

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[Bronchopulmonary dysplasia].

OBJECTIVE To present a wide-ranging review of the literature on broncopulmonary dysplasia, covering new definitions, pathophysiology, prevention, treatment, prognosis and progression. SOURCES OF DATA The most relevant articles published on the subject since it was first described in 1967 were selected from MEDLINE search results. SUMMARY OF THE FINDINGS Bronchopulmonary dysplasia is conside...

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Comparing the Efficacy of High and Low Doses of Vitamin A in Prevention of Bronchopulmonary Dysplasia

Background Bronchopulmonary dysplasia (BPD) is one of the most common serious squeal of preterm infants. It involves approximately one quarter of infants with birth weight less than 1500 grams and 30% of less than 1000 grams. Vitamin A has been shown to reduce BPD rate. We compared efficacy of low and high doses of vitamin A for prevention of BPD in very low birth weight preterm infants. Materi...

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ژورنال

عنوان ژورنال: Seminars in Perinatology

سال: 2013

ISSN: 0146-0005

DOI: 10.1053/j.semperi.2013.01.004